High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria

BACKGROUND: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. METHODOLOGY/PRINCIPAL FINDINGS: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as k(d)) of natur...

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Bibliografiske detaljer
Main Authors: Reddy, Sreenivasulu B., Anders, Robin F., Beeson, James G., Färnert, Anna, Kironde, Fred, Berenzon, Sharon Kühlman, Wahlgren, Mats, Linse, Sara, Persson, Kristina E. M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283742/
https://ncbi.nlm.nih.gov/pubmed/22363818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032242
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