Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time

Understanding the functional characteristics of naturally acquired antibodies against P. falciparum merozoite antigens is crucial for determining the protective functions of antibodies. Affinity (measured as k(d)) of naturally acquired antibodies against two key targets of acquired immunity, EBA175...

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Publicado en:Sci Rep
Autores principales: Tijani, Muyideen K., Reddy, Sreenivasulu B., Langer, Christine, Beeson, James G., Wahlgren, Mats, Nwuba, Roseangela I., Persson, Kristina E. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998021/
https://ncbi.nlm.nih.gov/pubmed/29899351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27361-w
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