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Matrix-Bound PAI-1 Supports Cell Blebbing via RhoA/ROCK1 Signaling

The microenvironment of a tumor can influence both the morphology and the behavior of cancer cells which, in turn, can rapidly adapt to environmental changes. Increasing evidence points to the involvement of amoeboid cell migration and thus of cell blebbing in the metastatic process; however, the cu...

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Bibliographic Details
Main Authors: Cartier-Michaud, Amandine, Malo, Michel, Charrière-Bertrand, Cécile, Gadea, Gilles, Anguille, Christelle, Supiramaniam, Ajitha, Lesne, Annick, Delaplace, Franck, Hutzler, Guillaume, Roux, Pierre, Lawrence, Daniel A., Barlovatz-Meimon, Georgia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283740/
https://ncbi.nlm.nih.gov/pubmed/22363817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032204
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