The GOAT-Ghrelin System Is Not Essential for Hypoglycemia Prevention during Prolonged Calorie Restriction

OBJECTIVE: Ghrelin acylation by ghrelin O-acyltransferase (GOAT) has recently been reported to be essential for the prevention of hypoglycemia during prolonged negative energy balance. Using a unique set of four different genetic loss-of-function models for the GOAT/ghrelin/growth hormone secretagog...

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Bibliografische gegevens
Hoofdauteurs: Yi, Chun-Xia, Heppner, Kristy M., Kirchner, Henriette, Tong, Jenny, Bielohuby, Maximillian, Gaylinn, Bruce D., Müller, Timo D., Bartley, Erin, Davis, Harold W., Zhao, Yongmei, Joseph, Anupama, Kruthaupt, Traci, Ottaway, Nickki, Kabra, Dhiraj, Habegger, Kirk M., Benoit, Stephen C., Bidlingmaier, Martin, Thorner, Michael O., Perez-Tilve, Diego, Tschöp, Matthias H., Pfluger, Paul T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283719/
https://ncbi.nlm.nih.gov/pubmed/22363801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032100
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