טוען...

Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions

Expansions of DNA trinucleotide repeats cause at least 17 inherited neurodegenerative diseases, such as Huntington's disease. Expansions can occur at frequencies approaching 100% in affected families and in transgenic mice, suggesting that specific cellular proteins actively promote (favor) exp...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Debacker, Kim, Frizzell, Aisling, Gleeson, Olive, Kirkham-McCarthy, Lucy, Mertz, Tony, Lahue, Robert S.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283555/
https://ncbi.nlm.nih.gov/pubmed/22363205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001257
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!