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Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element.
All human immunodeficiency virus mRNAs contain a sequence known as TAR (trans-activating responsive sequence). The TAR element forms a stable RNA stem-loop structure which binds the HIV tat (trans-activator) protein and mediates increased viral gene expression. In principle, molecules which bind to...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1991
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328335/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062653/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.12.3359 |
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