Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element.

All human immunodeficiency virus mRNAs contain a sequence known as TAR (trans-activating responsive sequence). The TAR element forms a stable RNA stem-loop structure which binds the HIV tat (trans-activator) protein and mediates increased viral gene expression. In principle, molecules which bind to...

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Päätekijät: Vickers, T, Baker, B F, Cook, P D, Zounes, M, Buckheit, R W, Germany, J, Ecker, D J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1991
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC328335/
https://ncbi.nlm.nih.gov/pubmed/2062653
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