Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element.

All human immunodeficiency virus mRNAs contain a sequence known as TAR (trans-activating responsive sequence). The TAR element forms a stable RNA stem-loop structure which binds the HIV tat (trans-activator) protein and mediates increased viral gene expression. In principle, molecules which bind to...

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Publicado en:	Nucleic Acids Res
Autores principales:	Vickers, T, Baker, B F, Cook, P D, Zounes, M, Buckheit, R W, Germany, J, Ecker, D J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1991
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328335/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062653/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.12.3359
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