Frameshift Signal Transplantation and the Unambiguous Analysis of Mutations in the Yeast Retrotransposon Ty1 Gag-Pol Overlap Region

The yeast retrotransposon Ty1 encodes a 7-nucleotide RNA sequence that directs a programmed, +1 ribosomal frameshifting event required for Gag-Pol translation and retrotransposition. We report mutations that block frameshifting, which can be suppressed in cis by “transplanting” the frameshift signal...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lawler, Joseph F., Merkulov, Gennady V., Boeke, Jef D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.6769-6775.2001
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