Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis

Genome-wide association studies (GWAS), although efficient to detect genes involved in complex diseases, are not designed to measure the real effect of the genes. This is illustrated here by the example of IL2RA in multiple sclerosis (MS). Association between IL2RA and MS is clearly established, alt...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Babron, Marie-Claude, Perdry, Hervé, Handel, Adam E, Ramagopalan, Sreeram V, Damotte, Vincent, Fontaine, Bertrand, Müller-Myhsok, Bertram, Ebers, George C, Clerget-Darpoux, Françoise
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283173/
https://ncbi.nlm.nih.gov/pubmed/22085902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.197
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares