Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia in HIV/HCV-Coinfected Patients With All HCV Genotypes

Background. A recent genome-wide association study reported a strong association with a single-nucleotide polymorphism (SNP) in the inosine triphosphate (ITPA) gene and hemolytic anemia in patients infected with hepatitis C virus (HCV) receiving pegylated interferon and ribavirin. We investigate the...

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Autores principales: Naggie, Susanna, Rallon, Norma I., Benito, José M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin V., Vispo, Eugenia, McHutchison, John G., Goldstein, David B., Soriano, Vincent
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283113/
https://ncbi.nlm.nih.gov/pubmed/22158703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir754
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