Control of Rapsyn Stability by the CUL-3-containing E3 Ligase Complex

Rapsyn is a postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. Here we report the mechanism for posttranslational control of rapsyn protein stability. We confirmed that C18H9.7-encoded RPY-1 is a rapsyn homolog in Caenorhabditis...

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Detalhes bibliográficos
Main Authors: Nam, Seunghee, Min, Kyoengwoo, Hwang, Hyejin, Lee, Hae-ock, Lee, Jung Hwa, Yoon, Jongbok, Lee, Hyunsook, Park, Sungsu, Lee, Junho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282941/
https://ncbi.nlm.nih.gov/pubmed/19158078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808230200
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