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Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration

AIMS: In atherosclerosis and restenosis, vascular smooth muscle cells (SMCs) migrate into the subendothelial space and proliferate, contributing to neointimal formation. The goal of this study was to define the signalling pathway by which Nox1 NAPDH oxidase mediates SMC migration. METHODS AND RESULT...

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Autors principals: Jagadeesha, Dammanahalli K., Takapoo, Maysam, Banfi, Botond, Bhalla, Ramesh C., Miller, Francis J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282575/
https://ncbi.nlm.nih.gov/pubmed/22102727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr308
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