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A Critical Role for ClC-3 in Smooth Muscle Cell Activation and Neointima Formation

OBJECTIVE: We have shown that the chloride-proton antiporter ClC-3 is required for endosome-dependent signaling by the Nox1 NADPH oxidase in SMCs. In this study, we tested the hypothesis that ClC-3 is necessary for proliferation of smooth muscle cells (SMCs) and contributes to neointimal hyperplasia...

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Detalhes bibliográficos
Main Authors: Chu, Xi, Filali, Mohammed, Stanic, Bojana, Takapoo, Maysam, Sheehan, Andrea, Bhalla, Ramesh, Lamb, Fred S., Miller, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025755/
https://ncbi.nlm.nih.gov/pubmed/21071705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.217604
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