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The ClC-3 Cl(−)/H(+) Antiporter Becomes Uncoupled at Low Extracellular pH
Adenovirus expressing ClC-3 (Ad-ClC-3) induces Cl(−)/H(+) antiport current (I(ClC-3)) in HEK293 cells. The outward rectification and time dependence of I(ClC-3) closely resemble an endogenous HEK293 cell acid-activated Cl(−) current (ICl(acid)) seen at extracellular pH ≤ 5.5. ICl(acid) was present i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807314/ https://ncbi.nlm.nih.gov/pubmed/19926787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018002 |
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