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Interaction of protein SRP19 with signal recognition particle RNA lacking individual RNA-helices.

Derivatives of human SRP-RNA were constructed by site-directed mutagenesis and tested for their ability to interact with protein SRP19. An RNA missing helix 6 barely interacts with SRP19, while the helix 8-deletion mutant retains much binding capability. A mutant RNA consisting just of helix 6 also...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Autor principal: Zwieb, C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1991
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1711676/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.11.2955
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