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Interaction of protein SRP19 with signal recognition particle RNA lacking individual RNA-helices.
Derivatives of human SRP-RNA were constructed by site-directed mutagenesis and tested for their ability to interact with protein SRP19. An RNA missing helix 6 barely interacts with SRP19, while the helix 8-deletion mutant retains much binding capability. A mutant RNA consisting just of helix 6 also...
Kaydedildi:
| Yazar: | |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1991
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC328257/ https://ncbi.nlm.nih.gov/pubmed/1711676 |
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