Interaction of protein SRP19 with signal recognition particle RNA lacking individual RNA-helices.
Derivatives of human SRP-RNA were constructed by site-directed mutagenesis and tested for their ability to interact with protein SRP19. An RNA missing helix 6 barely interacts with SRP19, while the helix 8-deletion mutant retains much binding capability. A mutant RNA consisting just of helix 6 also...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1991
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328257/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1711676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.11.2955 |
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