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Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Taq DNA polymerase.

A polymerase stop assay has been developed to determine the DNA nucleotide sequence specificity of covalent modification by antineoplastic agents using the thermostable DNA polymerase from Thermus aquaticus and synthetic labelled primers. The products of linear amplification are run on sequencing ge...

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Autors principals: Ponti, M, Forrow, S M, Souhami, R L, D'Incalci, M, Hartley, J A
Format: Artigo
Idioma:Inglês
Publicat: 1991
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC328253/
https://ncbi.nlm.nih.gov/pubmed/2057351
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