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Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Taq DNA polymerase.

A polymerase stop assay has been developed to determine the DNA nucleotide sequence specificity of covalent modification by antineoplastic agents using the thermostable DNA polymerase from Thermus aquaticus and synthetic labelled primers. The products of linear amplification are run on sequencing ge...

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Detalhes bibliográficos
Main Authors: Ponti, M, Forrow, S M, Souhami, R L, D'Incalci, M, Hartley, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC328253/
https://ncbi.nlm.nih.gov/pubmed/2057351
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