PAI-1 is an essential component of the pulmonary host response during Pseudomonas aeruginosa pneumonia in mice

RATIONALE: Elevated plasma and bronchoalveolar lavage fluid plasminogen activator inhibitor 1 (PAI-1) levels are associated with adverse clinical outcome in patients with pneumonia caused by Pseudomonas aeruginosa. However, whether PAI-1 plays a pathogenic role in the breakdown of the alveolar–capil...

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Hauptverfasser: Goolaerts, Arnaud, Lafargue, Mathieu, Song, Yuanlin, Miyazawa, Byron, Arjomandi, Mehrdad, Carlès, Michel, Roux, Jérémie, Howard, Marybeth, Parks, Dale A, Iles, Karen E, Pittet, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282176/
https://ncbi.nlm.nih.gov/pubmed/21768189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2010.155788
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