Cytoprotective-Selective Activated Protein C Attenuates Pseudomonas aeruginosa–Induced Lung Injury in Mice

Inhibition of the small GTPase RhoA attenuates the development of pulmonary edema and restores positive alveolar fluid clearance in a murine model of Pseudomonas aeruginosa pneumonia. Activated protein C (aPC) blocks the development of an unfavorably low ratio of small GTPase Rac1/RhoA activity in l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bir, Nastasha, Lafargue, Mathieu, Howard, Marybeth, Goolaerts, Arnaud, Roux, Jeremie, Carles, Michel, Cohen, Mitchell J., Iles, Karen E., Fernández, José A., Griffin, John H., Pittet, Jean-Francois
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175583/
https://ncbi.nlm.nih.gov/pubmed/21257925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0397OC
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados