The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain

The N-methyl-D-aspartate glutamate receptor (NMDAR) has been implicated in preterm brain injury (periventricular leukomalacia (PVL)) and represents a potential therapeutic target. However, the antagonist dizocilpine (MK-801) has been reported to increase constitutive neuronal apoptosis in the develo...

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Detaylı Bibliyografya
Asıl Yazarlar: Manning, Simon M., Boll, Griffin, Fitzgerald, Erin, Selip, Debra B., Volpe, Joseph J., Jensen, Frances E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282022/
https://ncbi.nlm.nih.gov/pubmed/21624454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2011.05.005
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