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The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain
The N-methyl-D-aspartate glutamate receptor (NMDAR) has been implicated in preterm brain injury (periventricular leukomalacia (PVL)) and represents a potential therapeutic target. However, the antagonist dizocilpine (MK-801) has been reported to increase constitutive neuronal apoptosis in the develo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282022/ https://ncbi.nlm.nih.gov/pubmed/21624454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijdevneu.2011.05.005 |
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