RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

Polycomb-repressive complex 1 (PRC1) has a central role in the regulation of heritable gene silencing during differentiation and development. PRC1 recruitment is generally attributed to interaction of the chromodomain of the core protein Polycomb with trimethyl histone H3K27 (H3K27me3), catalyzed by...

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Hlavní autoři: Tavares, Lígia, Dimitrova, Emilia, Oxley, David, Webster, Judith, Poot, Raymond, Demmers, Jeroen, Bezstarosti, Karel, Taylor, Stephen, Ura, Hiroki, Koide, Hiroshi, Wutz, Anton, Vidal, Miguel, Elderkin, Sarah, Brockdorff, Neil
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281992/
https://ncbi.nlm.nih.gov/pubmed/22325148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.12.029
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