Wordt geladen...

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

Transcription regulation involves enzyme-mediated changes in chromatin structure. Here, we describe a novel mode of histone crosstalk during gene silencing, in which histone H2A monoubiquitylation is coupled to the removal of histone H3 Lys 36 dimethylation (H3K36me2). This pathway was uncovered thr...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Lagarou, Anna, Mohd-Sarip, Adone, Moshkin, Yuri M., Chalkley, Gillian E., Bezstarosti, Karel, Demmers, Jeroen A.A., Verrijzer, C. Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569881/
https://ncbi.nlm.nih.gov/pubmed/18923078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.484208
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!