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dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing
Transcription regulation involves enzyme-mediated changes in chromatin structure. Here, we describe a novel mode of histone crosstalk during gene silencing, in which histone H2A monoubiquitylation is coupled to the removal of histone H3 Lys 36 dimethylation (H3K36me2). This pathway was uncovered thr...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2569881/ https://ncbi.nlm.nih.gov/pubmed/18923078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.484208 |
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