Chargement en cours...
Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons
Cofilin is an actin-binding protein and a major actin depolymerization factor in the central nervous system (CNS). Cofilin-actin aggregates are associated with neurodegenerative disorders, but how cofilin-actin aggregation induces pathological effects in the CNS remains unclear. Here, we demonstrate...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281697/ https://ncbi.nlm.nih.gov/pubmed/22184127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.301911 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|