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Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by the deposition of β-amyloid plaques in the brain. Plaques are composed of the amyloid-β peptide derived from cleavage of the amyloid precursor protein (APP). Mutations in APP lead to the development...

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Detalhes bibliográficos
Main Authors: Wiese, Mary, Antebi, Adam, Zheng, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942829/
https://ncbi.nlm.nih.gov/pubmed/20862215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012790
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