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Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by the deposition of β-amyloid plaques in the brain. Plaques are composed of the amyloid-β peptide derived from cleavage of the amyloid precursor protein (APP). Mutations in APP lead to the development...

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Autors principals: Wiese, Mary, Antebi, Adam, Zheng, Hui
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942829/
https://ncbi.nlm.nih.gov/pubmed/20862215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012790
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