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Dual Regulation of Notch1 Signaling Pathway by Adaptor Protein Fe65

Notch1 receptor functions as a critical controller of cell fate decisions and also as a key regulator of cell growth, differentiation, and proliferation in invertebrates and vertebrates. In this study, we have demonstrated that the adaptor protein Fe65 attenuates Notch1 signaling via the accelerated...

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Bibliographic Details
Main Authors: Kim, Mi-Yeon, Mo, Jung-Soon, Ann, Eun-Jung, Yoon, Ji-Hye, Park, Hee-Sae
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281649/
https://ncbi.nlm.nih.gov/pubmed/22199353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289637
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