NADPH Oxidase Is Internalized by Clathrin-coated Pits and Localizes to a Rab27A/B GTPase-regulated Secretory Compartment in Activated Macrophages

Here, we report that activation of different types of tissue macrophages, including microglia, by lipopolysaccharide (LPS) or GM-CSF stimulation correlates with the quantitative redistribution of NADPH oxidase (cyt b(558)) from the plasma membrane to an intracellular stimulus-responsive storage comp...

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Detalhes bibliográficos
Main Authors: Ejlerskov, Patrick, Christensen, Dan Ploug, Beyaie, David, Burritt, James B., Paclet, Marie-Helene, Gorlach, Agnes, van Deurs, Bo, Vilhardt, Frederik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281610/
https://ncbi.nlm.nih.gov/pubmed/22157766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293696
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