Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes

Cell polarity is essential for many cellular functions including division and cell-fate determination. Although RhoGTPase signaling and vesicle trafficking are both required for the establishment of cell polarity, the mechanisms by which they are coordinated are unclear. Here, we demonstrate that th...

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Detalhes bibliográficos
Main Authors: Mukherjee, Debarati, Sen, Arpita, Boettner, Douglas R., Fairn, Gregory D., Schlam, Daniel, Bonilla Valentin, Fernando J., Michael McCaffery, J., Hazbun, Tony, Staiger, Chris J., Grinstein, Sergio, Lemmon, Sandra K., Claudio Aguilar, R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795334/
https://ncbi.nlm.nih.gov/pubmed/23943876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.117663
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