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Topologically Conserved Residues Direct Heme Transport in HRG-1-related Proteins

Caenorhabditis elegans and human HRG-1-related proteins are conserved, membrane-bound permeases that bind and translocate heme in metazoan cells via a currently uncharacterized mechanism. Here, we show that cellular import of heme by HRG-1-related proteins from worms and humans requires strategicall...

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Detalhes bibliográficos
Main Authors: Yuan, Xiaojing, Protchenko, Olga, Philpott, Caroline C., Hamza, Iqbal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281596/
https://ncbi.nlm.nih.gov/pubmed/22174408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326785
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