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How a DNA polymerase clamp loader opens a sliding clamp
Processive chromosomal replication relies on sliding DNA clamps, which are loaded onto DNA by pentameric clamp loader complexes belonging to the AAA+ family of ATPases. We present structures for the ATP-bound state of the clamp loader complex from bacteriophage T4, bound to an open clamp and primer-...
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| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281585/ https://ncbi.nlm.nih.gov/pubmed/22194570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1211884 |
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