Antivascular Therapy for Multidrug-Resistant Ovarian Tumors by Macitentan, a Dual Endothelin Receptor Antagonist

Endothelin receptors (ETRs) are often overexpressed in ovarian tumors, which can be resistant to conventional therapies. Thus, we investigated whether blockage of the ETR pathways using the dual ETR antagonist macitentan combined with taxol or cisplatinum can produce therapy for orthotopically growi...

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Detalhes bibliográficos
Main Authors: Kim, Sun-Jin, Kim, Jang Seong, Kim, Seung Wook, Yun, Seok Joong, He, Junqin, Brantley, Emily, Fan, Dominic, Strickner, Panja, Lehembre, François, Regenass, Urs, Fidler, Isaiah J
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281406/
https://ncbi.nlm.nih.gov/pubmed/22348175
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