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Computational prediction of furin cleavage sites by a hybrid method and understanding mechanism underlying diseases
Furin cleaves diverse types of protein precursors in the secretory pathway. The substrates for furin cleavage possess a specific 20-residue recognition sequence motif. In this report, based on the functional characterisation of the 20-residue sequence motif, we developed a furin cleavage site predic...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281273/ https://ncbi.nlm.nih.gov/pubmed/22355773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00261 |
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