Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

SARS-CoV-2 has resulted in a global pandemic and shutdown economies around the world. Sequence analysis indicates that the novel coronavirus (CoV) has an insertion of a furin cleavage site (PRRAR) in its spike protein. Absent in other group 2B CoVs, the insertion may be a key factor in the replicati...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:bioRxiv
Main Authors: Johnson, Bryan A., Xie, Xuping, Kalveram, Birte, Lokugamage, Kumari G., Muruato, Antonio, Zou, Jing, Zhang, Xianwen, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Bopp, Nathen, Schindewolf, Craig, Vu, Michelle, Vanderheiden, Abigail, Swetnam, Daniele, Plante, Jessica A., Aguilar, Patricia, Plante, Kenneth S., Lee, Benhur, Weaver, Scott C., Suthar, Mehul S., Routh, Andrew L., Ren, Ping, Ku, Zhiqiang, An, Zhiqiang, Debbink, Kari, Shi, Pei Yong, Freiberg, Alexander N., Menachery, Vineet D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457603/
https://ncbi.nlm.nih.gov/pubmed/32869021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.26.268854
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים