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Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris

BACKGROUND: Proprotein convertase furin is responsible for the processing of a wide variety of precursors consisted of signal peptide, propeptide and mature peptide in mammal. Many precursors processed by furin have important physiological functions and can be recombinantly expressed in Pichia pasto...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Huang, Yide, Long, Yanyu, Li, Suhuan, Lin, Ting, Wu, Jingwen, Zhang, Yafei, Lin, Yao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223083/
https://ncbi.nlm.nih.gov/pubmed/30409181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1020-x
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