Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris

BACKGROUND: Proprotein convertase furin is responsible for the processing of a wide variety of precursors consisted of signal peptide, propeptide and mature peptide in mammal. Many precursors processed by furin have important physiological functions and can be recombinantly expressed in Pichia pasto...

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Publicado en:Microb Cell Fact
Autores principales: Huang, Yide, Long, Yanyu, Li, Suhuan, Lin, Ting, Wu, Jingwen, Zhang, Yafei, Lin, Yao
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223083/
https://ncbi.nlm.nih.gov/pubmed/30409181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1020-x
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