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A Simplified and Efficient Process for Insulin Production in Pichia pastoris

A significant barrier to insulin is affordability. In this manuscript we describe improvements to key steps in the insulin production process in Pichia pastoris that reduce cost and time. The strategy for recovery and processing of human insulin precursor has been streamlined to two steps from biore...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Polez, Sulena, Origi, Domenico, Zahariev, Sotir, Guarnaccia, Corrado, Tisminetzky, Sergio G., Skoko, Nataša, Baralle, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131935/
https://ncbi.nlm.nih.gov/pubmed/27907132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167207
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