Quinol derivatives as potential trypanocidal agents

Quinols have been developed as a class of potential anti-cancer compounds. They are thought to act as double Michael acceptors, forming two covalent bonds to their target protein(s). Quinols have also been shown to have activity against the parasite Trypanosoma brucei, the causative organism of huma...

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Bibliografiska uppgifter
Huvudupphovsmän: Capes, Amy, Patterson, Stephen, Wyllie, Susan, Hallyburton, Irene, Collie, Iain T., McCarroll, Andrew J., Stevens, Malcolm F.G., Frearson, Julie A., Wyatt, Paul G., Fairlamb, Alan H., Gilbert, Ian H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Science 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281193/
https://ncbi.nlm.nih.gov/pubmed/22264753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.12.018
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