Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

Visceral leishmaniasis is a neglected tropical disease with significant health impact. The current treatments are poor, and there is an urgent need to develop new drugs. Primary screening assays used for drug discovery campaigns have typically used free-living forms of the Leishmania parasite to all...

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Autori principali: De Rycker, Manu, Hallyburton, Irene, Thomas, John, Campbell, Lorna, Wyllie, Susan, Joshi, Dhananjay, Cameron, Scott, Gilbert, Ian H., Wyatt, Paul G., Frearson, Julie A., Fairlamb, Alan H., Gray, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Susceptibility
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697379/
https://ncbi.nlm.nih.gov/pubmed/23571538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02398-12
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