Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells

Marrow stromal cells (MSCs) isolated from mesenchymal tissues can propagate in vitro to some extent and differentiate into various tissue lineages to be used for cell-based therapies. Cellular senescence, which occurs readily in continual MSC culture, leads to loss of these characteristic properties...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kanehira, Masahiko, Kikuchi, Toshiaki, Ohkouchi, Shinya, Shibahara, Taizou, Tode, Naoki, Santoso, Arif, Daito, Hisayoshi, Ohta, Hiromitsu, Tamada, Tsutomu, Nukiwa, Toshihiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281120/
https://ncbi.nlm.nih.gov/pubmed/22359668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032185
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