Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells

Marrow stromal cells (MSCs) isolated from mesenchymal tissues can propagate in vitro to some extent and differentiate into various tissue lineages to be used for cell-based therapies. Cellular senescence, which occurs readily in continual MSC culture, leads to loss of these characteristic properties...

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Bibliografische gegevens
Hoofdauteurs: Kanehira, Masahiko, Kikuchi, Toshiaki, Ohkouchi, Shinya, Shibahara, Taizou, Tode, Naoki, Santoso, Arif, Daito, Hisayoshi, Ohta, Hiromitsu, Tamada, Tsutomu, Nukiwa, Toshihiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281120/
https://ncbi.nlm.nih.gov/pubmed/22359668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032185
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