Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells

Marrow stromal cells (MSCs) isolated from mesenchymal tissues can propagate in vitro to some extent and differentiate into various tissue lineages to be used for cell-based therapies. Cellular senescence, which occurs readily in continual MSC culture, leads to loss of these characteristic properties...

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Główni autorzy: Kanehira, Masahiko, Kikuchi, Toshiaki, Ohkouchi, Shinya, Shibahara, Taizou, Tode, Naoki, Santoso, Arif, Daito, Hisayoshi, Ohta, Hiromitsu, Tamada, Tsutomu, Nukiwa, Toshihiro
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2012
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281120/
https://ncbi.nlm.nih.gov/pubmed/22359668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032185
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