Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells

Marrow stromal cells (MSCs) isolated from mesenchymal tissues can propagate in vitro to some extent and differentiate into various tissue lineages to be used for cell-based therapies. Cellular senescence, which occurs readily in continual MSC culture, leads to loss of these characteristic properties...

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Detalles Bibliográficos
Autores principales: Kanehira, Masahiko, Kikuchi, Toshiaki, Ohkouchi, Shinya, Shibahara, Taizou, Tode, Naoki, Santoso, Arif, Daito, Hisayoshi, Ohta, Hiromitsu, Tamada, Tsutomu, Nukiwa, Toshihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281120/
https://ncbi.nlm.nih.gov/pubmed/22359668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032185
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