Mesenchymal Stromal Cells Protect Cancer Cells From ROS-induced Apoptosis and Enhance the Warburg Effect by Secreting STC1

Previous studies have demonstrated that mesenchymal stromal cells (MSCs) enhance cell survival through upregulation and secretion of stanniocalcin-1 (STC1). This study shows that MSC-derived STC1 promotes survival of lung cancer cells by uncoupling oxidative phosphorylation, reducing intracellular r...

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Detalhes bibliográficos
Main Authors: Ohkouchi, Shinya, Block, Gregory J, Katsha, Ahmed M, Kanehira, Masahiko, Ebina, Masahito, Kikuchi, Toshiaki, Saijo, Yasuo, Nukiwa, Toshihiro, Prockop, Darwin J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277221/
https://ncbi.nlm.nih.gov/pubmed/22146344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.259
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