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A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity

Due to the inexorable invasion of our hospitals and communities by drug-resistant bacteria, there is a pressing need for novel antibacterial agents. Here we report the development of a sensitive and robust but low-tech and inexpensive high-throughput metabolic screen for novel antibiotics. This scre...

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Detalhes bibliográficos
Main Authors: Ymele-Leki, Patrick, Cao, Shugeng, Sharp, Jared, Lambert, Kathleen G., McAdam, Alexander J., Husson, Robert N., Tamayo, Giselle, Clardy, Jon, Watnick, Paula I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281070/
https://ncbi.nlm.nih.gov/pubmed/22359585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031307
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