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Axinellamines as Broad-Spectrum Antibacterial Agents: Scalable Synthesis and Biology

[Image: see text] Antibiotic-resistant bacteria present an ongoing challenge to both chemists and biologists as they seek novel compounds and modes of action to out-maneuver continually evolving resistance pathways, especially against Gram-negative strains. The dimeric pyrrole–imidazole alkaloids re...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Rodriguez, Rodrigo A., Barrios Steed, Danielle, Kawamata, Yu, Su, Shun, Smith, Peter A., Steed, Tyler C., Romesberg, Floyd E., Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227811/
https://ncbi.nlm.nih.gov/pubmed/25328977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508632y
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