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Effects of Inhibiting CoQ(10) Biosynthesis with 4-nitrobenzoate in Human Fibroblasts

Coenzyme Q(10) (CoQ(10)) is a potent lipophilic antioxidant in cell membranes and a carrier of electrons in the mitochondrial respiratory chain. We previously characterized the effects of varying severities of CoQ(10) deficiency on ROS production and mitochondrial bioenergetics in cells harboring ge...

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Autors principals: Quinzii, Catarina M., Tadesse, Saba, Naini, Ali, Hirano, Michio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281033/
https://ncbi.nlm.nih.gov/pubmed/22359546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030606
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