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A Race between Tumor Immunoescape and Genome Maintenance Selects for Optimum Levels of (epi)genetic Instability

The human immune system functions to provide continuous body-wide surveillance to detect and eliminate foreign agents such as bacteria and viruses as well as the body's own cells that undergo malignant transformation. To counteract this surveillance, tumor cells evolve mechanisms to evade elimi...

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Detalhes bibliográficos
Main Authors: Iwami, Shingo, Haeno, Hiroshi, Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280962/
https://ncbi.nlm.nih.gov/pubmed/22359489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002370
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