Depletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosis

Tissue factor (TF) is a significant risk factor for hepatic metastasis in patients with colorectal cancer (CRC). However, the mechanism by which TF promotes hepatic metastasis in CRC remains elusive. In this study, we first confirmed that TF expression was significantly correlated with lymph node me...

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Bibliografiska uppgifter
Huvudupphovsmän: Tian, Maolin, Wan, Yuanlian, Tang, Jianqiang, Li, Hui, Yu, Ge, Zhu, Jing, Ji, Shiqi, Guo, Hui, Zhang, Nan, Li, Weiren, Gai, Junwei, Wang, Lei, Dai, Lifang, Liu, Die, Lei, Liandi, Zhu, Shigong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2011
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280905/
https://ncbi.nlm.nih.gov/pubmed/22052255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.10.17679
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