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Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state T(H)17 cells in the intestine

T(H)17 cells are a lineage of CD4(+) T cells that are critical for host defense and autoimmunity by expressing the cytokines IL-17A, IL-17F, and IL-22. A feature of T(H)17 cells at steady state is their ubiquitous presence in the lamina propria of the small intestine. The induction of these steady-s...

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Bibliografiska uppgifter
Huvudupphovsmän: Shaw, Michael H., Kamada, Nobuhiko, Kim, Yun-Gi, Núñez, Gabriel
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280878/
https://ncbi.nlm.nih.gov/pubmed/22291094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111703
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