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Breakage of single-stranded DNA by rat liver nicking-closing enzyme with the formation of a DNA-enzyme complex.

The DNA nicking-closing enzyme (type I topoisomerase) from rat liver nuclei breaks single-stranded DNA. The broken strand contains a 5'-hydroxyl and tightly bound protein. The stability of this protein-DNA complex to high salt, alkali and detergent suggests a covalent linkage between the DNA and the...

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Publicat a:Nucleic Acids Res
Autors principals: Been, M D, Champoux, J J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1980
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6258163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.24.6129
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